Long chain n-3 polyunsaturated fatty acids reduce atrial vulnerability in a novel canine pacing model

Long chain n-3 polyunsaturated fatty acids reduce atrial vulnerability in a novel canine pacing model.

AIM Our objective was to assess the effect of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on atrial fibrillation (AF) vulnerability and atrial structure in a new model of atrial cardiomyopathy. METHODS AND RESULTS Dogs were studied in three groups: seven control dogs (UNPACED) and 24 dogs undergoing simultaneous atrioventricular pacing (for 2 weeks) assigned to placebo treatment (SAVP-PLA...

comparison of long chain and medium chain polyunsaturated n-3 fatty acids for their ability to correct insulin resistance induced by saturated fatty acids in cultured bovine adipocytes

background: the modern dairy cows, due to intensive selection for higher milk production during past decades, have become more resistant to insulin. accompanied with dmi depression in per parturient dairy cow, insulin resistance may lead to a massive release of non-esterified fatty acids (nefa) to bloodstream which might act as a start point for development of other diseases. objectives: the pu...

Omega-3 Long Chain Polyunsaturated Fatty Acids as Sensitizing

The efficacy of chemotherapy depends on sensitivity and intrinsic or acquired drug 14 resistance of cancer cells. The n-3 long chain polyunsaturated fatty acids (n-3 LCPUFAs) are 15 considered chemosensitizing agents and revertants of multidrug resistance by pleiotropic 16 mechanisms. The specific mechanisms are not fully understood, but nowadays, it is widely accepted 17 that there are a compl...

A Novel Long Chain Polyunsaturated Fatty

Dietary Fish and Long-Chain n-3 Polyunsaturated Fatty Acids Intake and Risk of Atrial Fibrillation: A Meta-Analysis

Findings on the association between long-term intake of fish or long-chain n-3 polyunsaturated fatty acids (PUFAs) and risk of atrial fibrillation (AF) are inconsistent in observational studies. We conducted a meta-analysis of prospective studies to separately examine the associations between fish consumption and dietary intake of n-3 PUFAs with the risk of AF. A systematic search was conducted...